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KMID : 1143620150190020081
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Korean Journal of Nuclear Medicine Technology
2015 Volume.19 No. 2 p.81 ~ p.86
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Usefulness of the quantitative analysis by using the functional parameter index from dynamic salivary glands scintigraphy
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Shin Chae-Ho
Kim Bong-Soo
Jo Yong-Gwi
Cho Jin-Woo
Jin Sung-Eun
Pyo Seong-Jae
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Abstract
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Purpose : This study was to evaluate the usefulness through the comparison of patients group and healthy control group by acquiring a variety of functional parameters index from time-activity curves of salivary gland scintigraphy using 99 mc.
Materials and Methods : From December 2014 to February 2015 with the targets of 30 patients in the patient group who presented themselves with xerostomia and underwent the salivary gland scan and 10 people in healthy control group, approximately 30 minutes of dynamic Scan was carried out after the intravenous bolus injection of 370 MBq of 99mTcO_4- and per os stimulation with Vitamin C powder 20 minutes after the injection. The method of quantitative analysis was as follows, the time-activity curve was drawn after the parotid gland and submandible gland were prescribed as a region of interest, a variety of functional parameters index was obtained in each position of the curve, and the patients group and the control group were compared.
Results : As for the methods applied in comparison and measurement, uptake ratio (UR), time at maximum counts (Tmax), time at minimum counts (Tmin), maximum accumulation (MA), accumulation velocity, maximum secretion (MS), maximum stimulation secretion (MSS), and secretion velocity (SV) were used. In the comparison of functional parameters index of patient group and normal group, the healthy normal group showed significant difference compared to the patient group in all indices except for the minimum radioactivity time (Tmin), and also in terms of variation over time the normal group showed significant difference compared to the patient group (p<0.05).
Conclusion : Consequently, it was considered that the quantitative analysis that used a variety of functional parameters index would be useful for evaluating the function of the salivary glands of the patients with xerostomia as an objective and standardized information.
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KEYWORD
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Dynamic Salivary Gland Scintigraphy, Functional Parameter Index, Quantitative analysis, Xerostomia
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